Structural determinants of efficacy for kappa opioid receptors in the orvinol series: 7,7-spiro analogues of buprenorphine

J Med Chem. 2000 Jan 27;43(2):139-41. doi: 10.1021/jm991165p.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Analgesics, Opioid / pharmacology*
  • Animals
  • Buprenorphine / analogs & derivatives*
  • Buprenorphine / chemistry
  • Buprenorphine / pharmacology
  • CHO Cells
  • Cricetinae
  • Molecular Structure
  • Receptors, Opioid, kappa / drug effects*

Substances

  • Analgesics, Opioid
  • Receptors, Opioid, kappa
  • Buprenorphine